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Multiple Choice

How does the severity of trichinellosis vary?

Severity is driven by the parasite load ingested. In trichinellosis, eating meat containing Trichinella larvae starts a chain where larvae mature and reproduce, and many larvae migrate to and encyst in muscle tissue. The greater the number of larvae that enter this process, the larger the parasite burden and the stronger the inflammatory response, leading to more pronounced symptoms such as fever, muscle pain and weakness, swelling, and higher eosinophil levels. A small dose may cause mild illness or be asymptomatic. While the type of meat or how it’s cooked can affect whether exposure occurs or larvae survive, the main factor determining how severe the illness will be once infection happens is how many parasites were ingested.

Severity is driven by the parasite load ingested. In trichinellosis, eating meat containing Trichinella larvae starts a chain where larvae mature and reproduce, and many larvae migrate to and encyst in muscle tissue. The greater the number of larvae that enter this process, the larger the parasite burden and the stronger the inflammatory response, leading to more pronounced symptoms such as fever, muscle pain and weakness, swelling, and higher eosinophil levels. A small dose may cause mild illness or be asymptomatic. While the type of meat or how it’s cooked can affect whether exposure occurs or larvae survive, the main factor determining how severe the illness will be once infection happens is how many parasites were ingested.